Free tool · Private
Check your 23andMe or AncestryDNA raw data for testosterone and hormone genes
Open your raw DNA file and see your genotype at 14 studied variants in 7 hormone-related genes, each with what researchers found and how strong the evidence is. Your file is read on your device and never uploaded.
- Works with
- 23andMe, AncestryDNA, MyHeritage, FTDNA and Living DNA raw data, as .txt, .csv or the .zip you downloaded.
- Genes
- SHBG, CYP19A1, SRD5A2, AR, EDA2R, ESR1, CYP3A4
- Privacy
- Read in your browser. Nothing is uploaded or stored.
- Can't show
- The androgen receptor CAG repeat length or the UGT2B17 deletion. Chips don't measure them.
- Cost
- Free, no account.
How to download your raw data
- 23andMe: Settings, then 23andMe Data, then request your raw data. You get an email when the .zip is ready.
- AncestryDNA: DNA, then Settings, then Download DNA data. The file arrives as a .zip.
- MyHeritage: DNA, then Manage DNA kits, then Download raw DNA data.
Open the .zip as it is, or the .txt or .csv inside it.
The variants it looks for
These are the hormone-gene variants that consumer chips usually include and that published studies have looked at. Evidence is rated from Well replicated (large studies, replicated) through Some evidence to Early research (small, inconsistent or not about hormones in men). We only say which allele does what where the study names it.
| Gene | Variant | Evidence |
|---|---|---|
| SHBG | Near the SHBG gene (rs12150660) | Well replicated |
| SHBG | SHBG P156L (rs6258) | Well replicated |
| SHBG | SHBG promoter (−68 G>A) (rs1799941) | Some evidence |
| SHBG | SHBG +1091 C>T (rs727428) | Early research |
| SHBG | SHBG D356N (rs6259) | Early research |
| CYP19A1 | Aromatase, intron 1 (rs2470152) | Well replicated |
| CYP19A1 | Aromatase V80 (rs700518) | Some evidence |
| CYP19A1 | Aromatase 3′ UTR (rs10046) | Early research |
| SRD5A2 | 5-alpha reductase V89L (rs523349) | Early research |
| AR | Androgen receptor E211E (rs6152) | Some evidence |
| EDA2R | Next to the androgen receptor (rs1385699) | Some evidence |
| ESR1 | Oestrogen receptor PvuII (rs2234693) | Early research |
| ESR1 | Oestrogen receptor XbaI (rs9340799) | Early research |
| CYP3A4 | CYP3A4*22 (rs35599367) | Early research |
What your raw data can’t show
Genotyping chips, the technology behind 23andMe and AncestryDNA, read single-letter variants. They don’t readily capture repeat lengths.[1] Two of the most studied hormone-gene differences are exactly that kind:
- The androgen receptor CAG repeat, a run of repeated letters whose length varies between men.
- The UGT2B17 deletion, where a 117,000-letter stretch containing the whole gene is missing from one or both copies of chromosome 4.
Chips are accurate for common variants, but much less so for very rare ones, which is why raw-data findings shouldn’t guide health decisions without confirmation.[2]
Questions
Can I check my 23andMe raw data for testosterone genes?
Yes, for some of them. Download your raw data from 23andMe (Settings, then 23andMe Data), open the file here, and you will see your genotype at 14 studied variants in SHBG, CYP19A1, SRD5A2, AR, EDA2R, ESR1, CYP3A4, where your chip included them. The file is read in your browser and never uploaded.
Is my DNA file uploaded anywhere?
No. The page reads the file with your browser's own code and looks up a short list of variants. Nothing is sent to GeneticEdge or anyone else, and nothing is kept when you close the page.
Can my raw data show my androgen receptor CAG repeats?
No. Genotyping chips read single-letter variants (SNPs). They don't read repeat lengths, so the androgen receptor's CAG repeat needs a test that measures it directly, by fragment analysis or sequencing.
Can it show the UGT2B17 deletion?
Not reliably. The UGT2B17 deletion removes a whole stretch of DNA, and consumer chips aren't designed to count copies of it. A targeted test is needed.
What does a 'Not in your file' result mean?
Your company's chip didn't include that variant, or couldn't read it in your sample. Chips differ between companies and versions, so some variants will be missing.
Should I act on these results?
No. They are associations from studies of groups of people, mostly with small effects, and raw data from consumer chips can contain errors, especially for rare variants. They can't tell you your hormone levels or whether anything is safe for you.
Sources
- Saini S et al. A reference haplotype panel for genome-wide imputation of short tandem repeats. Nat Commun 2018;9:4397.
- Weedon MN et al. Use of SNP chips to detect rare pathogenic variants: retrospective, population based diagnostic evaluation. BMJ 2021;372:n214.
- Xue Y et al. Adaptive evolution of UGT2B17 copy-number variation. Am J Hum Genet 2008;83:337–46.
- Ohlsson C et al. PLoS Genet 2011 (8,938 men)
- Grigorova M et al. J Endocr Soc 2017
- Coviello AD et al. PLoS Genet 2012
- Eriksson AL et al. J Clin Endocrinol Metab 2009
- Peter I et al. J Clin Endocrinol Metab 2008
- Travis RC et al. Cancer Epidemiol Biomarkers Prev 2009
- Makridakis N et al. Cancer Res 1997
- Hillmer AM et al. Am J Hum Genet 2005
- Heilmann-Heimbach S et al. Nat Commun 2017
- Ioannidis JPA et al. JAMA 2004
- Review of CYP3A4*22, PMC4674354
Keep reading
- Guides
Androgen receptor CAG repeats
The AR gene's CAG repeat: what it is, what studies link it to, and how it is tested in the UK.
- Guides
Genetics of steroid response
Which genes have been studied in connection with testosterone and anabolic steroids, and how strong the evidence is.
- Compare
23andMe vs GeneticEdge
23andMe against a targeted hormone-gene test: what each reads, price and privacy after the sale.
For information only, not medical advice. GeneticEdge does not recommend or endorse anabolic steroid use, and no genetic test can tell you whether steroids are safe for you. Talk to a GP or pharmacist about your health. Last reviewed 30 October 2026.